SELECTED PAPERS

• A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRviii, and PI3KCAH1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo.
  Alex Weiss, Cassandra D’Amata, Bret J. Pearson*, Madeline N. Hayes*
  eLife. 2024 https://elifesciences.org/articles/93077.

• Planarians require ced-12/elmo-1 to clear dead cells by excretion through the gut.
  Lindsay-Mosher N, Lusk, S, and Pearson BJ
  Cell Reports. 2024 43(1):113621. doi: 10.1016/j.celrep.2023.113621

• The BAF chromatin remodeling complex licenses planarian stem cells access to ectodermal and mesodermal cell fates .
  Mallory Wiggans, Shu Jun Zhu, Alyssa M. Molinaro, and Bret J Pearson
  BMC Biology. 2023 21(1):227. doi: 10.1186/s12915-023-01730-y

• aristaless-like homeobox-3 is wound induced and promotes a low-Wnt environment required for planarian head regeneration .
  Zaleena Akheralie, Tanner J. Scidmore, and Bret J Pearson.
  Development. 2023 150(18):dev201777. doi: 10.1242/dev.201777

• The DEAD-box helicase DDX56 is a highly-conserved stemness regulator in normal and cancer stem cells.
  Michael Pryszlak*, Mallory Wiggans*, Xin Chen, Julia E. Jaramillo, Sarah E. Burns, Laura Richards, Trevor J. Pugh, David R. Kaplan, Xi Huang, Peter B. Dirks, and Bret J. Pearson.
  Cell Reports. 2021 34(13):108903. doi: 10.1016/j.celrep.2021.108903

• Yorkie is required to restrict the injury responses in planarians.
  Lin AYT, Pearson BJ.
  PLoS Genetics. 2017; 13(7):e1006874.

• A Brain Unfixed: Unlimited Neurogenesis and Regeneration of the Adult Planarian Nervous System.
  Brown DDR, Pearson BJ.
  Frontiers in Neuroscience. 2017; 11:289.

• Neuronal sources of hedgehog modulate neurogenesis in the adult planarian brain.
  Currie KW, Molinaro AM, Pearson BJ.
  eLife. 2016 Nov 19;5.

• In silico lineage tracing through single cell transcriptomics identifies a neural stem cell population in planarians.
  Molinaro AM, Pearson BJ.
  Genome Biology. 2016 Apr 27;17:87.

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